Pipeline

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The Fever Encounter:

A few sentences explaining the fever encounter.

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Dilemma 1:

O’Neill, The AMR Report, 2016

Dilemma 2:

https://www.cdc.gov/sepsis/clinicaltools/index.html 

https://journals.lww.com/ccmjournal/Fulltext/2020/03000/Sepsis_Among_Medicare_Beneficiaries 

https://www.nejm.org/doi/full/10.1056/nejmoa1703058

Dilemma 3:

Chousterman BG, Swirski FK, Weber GF. Cytokine storm and sepsis disease pathogenesis. Semin Immunopathol. 2017 Jul;39(5):517-528. doi: 10.1007/s00281-017-0639-8. Epub 2017 May 29. PMID: 28555385.

Tay MZ, Poh CM, Rénia L, MacAry PA, Ng LFP. The trinity of COVID-19: immunity, inflammation and intervention. Nat Rev Immunol. 2020 Jun;20(6):363-374. doi: 10.1038/s41577-020-0311-8. Epub 2020 Apr 28. PMID: 

Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG. Into the eye of the cytokine storm. Microbiol Mol Biol Rev. 2012 Mar;76(1):16-32. doi: 10.1128/MMBR.05015-11. PMID: 22390970; PMCID: PMC3294426.32346093; PMCID: PMC7187672.