Journal Publications
European Journal of Clinical Microbiology & Infectious Diseases
A host-protein signature is superior to other biomarkers for differentiating between bacterial and viral disease in patients with respiratory infection and fever without source: a prospective observational study.
Ashkenazi-Hoffnung L, Oved K, Navon R, Friedman T, Boico O, Paz M, Kronenfeld G, Etshtein L, Cohen A, Gottlieb TM, Eden E, Chistyakov I, Srugo I, Klein A, Ashkenazi S, Scheuerman O.
Eur J Clin Microbiol Infect Dis. 2018 Apr 26. doi: 10.1007/s10096-018-3261-3
Diagnostic Microbiology & Infectious Disease
A novel host-protein assay outperforms routine parameters for distinguishing between bacterial and viral lower respiratory tract infections.
Stein M, Lipman-Arens S, Oved K, Cohen A, Bamberger E, Navon R, Boico O, Friedman T, Etshtein L, Paz M, Gottlieb TM, Kriger O, Fonar Y, Pri-Or E, Yacobov R, Dotan Y, Hochberg A, Grupper M, Chistyakov I, Potasman I, Srugo I, Eden E, Klein A
Diagn Microbiol Infect Dis. 2018 Mar;90(3):206-213. doi: 10.1016/j.diagmicrobio.2017.11.011
Lancet Infectious Diseases
A Host-Protein Based Assay to Differentiate between Bacterial and Viral Infections in Preschool Children (OPPORTUNITY): A Double-Blind, Multicentre, Validation Study.
van Houten CB, de Groot JAH, Klein A, Srugo I, Chistyakov I, de Waal W, Meijssen CB, Avis W, Wolfs TFW, Shachor-Meyouhas Y, Stein M, Sanders EAM, Bont LJ
Lancet Infect Dis. 2017 Apr;17(4):431-440. doi: 10.1016/S1473-3099(16)30519-9
Srugo I, Klein A, Stein M, Golan-Shany O, Kerem N, Chistyakov I, Genizi J, Glazer O, Yaniv L, German A, Miron D, Shachor-Meyouhas Y, Bamberger E, Oved K, Gottlieb TM, Navon R, Paz M, Etshtein L, Boico O, Kronenfeld G, Eden E, Cohen R, Chappuy H, Angoulvant F, Lacroix L, Gervaix A
Pediatrics. 2017 Oct;140(4). pii: e20163453. doi: 10.1542/peds.2016-3453
Journal of Infection
Diagnostic Accuracy of a TRAIL, IP-10 and CRP Combination for Discriminating Bacterial and Viral Etiologies at the Emergency Department.
Eden E, Srugo I, Gottlieb T, Navon R, Boico O, Cohen A, Bamberger E, Klein A, Oved K
J Infect. 2016 Aug;73(2):177-80. doi: 10.1016/j.jinf.2016.05.002
PLOS ONE
A Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infections.
Oved K, Cohen A, Boico O, Navon R, Friedman T, Etshtein L, Kriger O, Bamberger E, Fonar Y, Yacobov R, Wolchinsky R, Denkberg G, Dotan Y, Hochberg A, Reiter Y, Grupper M, Srugo I, Feigin P, Gorfine M, Chistyakov I, Dagan R, Klein A, Potasman I, Eden E.
PLoS One. 2015 Mar 18;10(3):e0120012. doi: 10.1371/journal.pone.0120012
Future Microbiology
A Multifaceted ‘omics’ Approach for Addressing The Challenge of Antimicrobial Resistance.
Cohen A, Bont L, Engelhard D, Moore E, Fernández D, Kreisberg-Greenblatt R, Oved K, Eden E, Hays JP
Future Microbiol. 2015;10(3):365-76. doi: 10.2217/fmb.14.127
Future Science
Automating a New Host-protein Assay for Differentiating Bacterial from Viral Infection to Reduce Operator Hands-on time.
Shapira M, Boico O, Cohen A, Sagi R, Aharon A, Navon R, Kronenfeld G, Maler K, Pri-Or E, Stein M, Klein A, Eden E, Oved K
BioTechniques. 2018 Aug;65:93-95. doi: 10.2144/btn-2018-0028
International
Conferences
ID week 2018 - San Francisco, USA
Using the host immune response to identify viral-bacterial coinfection in children with respiratory syncytial virus infection.
Oral presentation
A host-response assay distinguishes between simple influenza patients and patients with bacterial coinfection.
ECCMID 2018 - Madrid, Spain
Evaluating performance and utility of a novel host-protein assay in mild acute infections.
Oral presentation
ESPID 2018 Malmo, Sweden
Determining viral etiology: TRAIL biomarker levels and molecular viral detection in the AutoPilot-Dx study.
TRAIL, IP-10, CRP, and ImunnoXpert™ levels in children with acute respiratory tract infections - an interim analysis from the AutoPilot-Dx study.
Evaluating the potential clinical utility of a host-protein signature for distinguishing between bacterial and viral disease in febrile children.
ESPID 2017 - Madrid, Spain
Evaluating a novel host-immune based assay for distinguishing bacterial from various viral infections in febrile children.
Selected best e-poster presentation
AACC 2017 - San Diego, USA
Evaluating a novel host immune-based assay for distinguishing bacterial from various viral infections in febrile children.
ID Week 2017 - San Diego, USA
A novel host-protein assay accurately distinguishes bacterial from viral upper respiratory tract infections.
Molecular Dx Europe - Lisbon, Portugal
Redefining the set of solutions for antibiotics misuse using host response-based diagnostics.
A podcast by Dr. Kfir Oved
ECCMID 2016 - Amsterdam, Netherlands
A novel host-protein signature outperforms standard
laboratory parameters in the differential diagnosis of lower respiratory tract infections.
DLD Conference 2016 - Munich, Germany
When The Drugs Don´t Work
Pioneer Eran Eden and his MeMed team from Israel invented the impossible – a bloodtest that tells you if you are suffering from a bacterial or a viral infection and whether you should be treated with antibiotics or a simple chicken soup.
ID Week 2016 - New Orleans, USA
TNF-related apoptosis-inducing ligand (TRAIL) protein as a marker for disease severity in patients with acute infection.
A Novel Immunoassay that distinguishes between Bacterial and Viral Infections Based on a Patient’s Immune Response.
Distinguished abstract award
AACC 2015 - Atlanta, USA
ID Week 2015 - San Diego, USA
A Novel Host-Protein Signature Outperforms Standard Laboratory Parameters in Differential Diagnosis of Acute Infection Etiology of Febrile Children.
EuroMedLab 2015 - Paris, France
Automated ELISA measurements of host-immune biomarkers for distinguishing between acute bacterial and viral infections.
ICAAC 2015 - San Diego, USA
Validation of a novel host response based assay for diagnosis of acute infectious etiology in febrile children: a blinded retrospective observational study.
ESPID 2015 - Leipzig, Germany
Combining viral- and bacterial-induced host proteins for diagnosing serious bacterial infections in febrile children.
WSPID 2015 - Rio de Janeiro, Brazil
Mapping the co-occurrence of bacteria and viruses in healthy and febrile children.
ESPID 2014 - Dublin, Ireland
A novel host-proteome signature to distinguish between acute bacterial and viral infections in febrile children.
