Publications
PUBLICATION: Bacterial vs Viral Etiology of Fever: A Prospective Study of a Host Score for Supporting Etiologic Accuracy of Emergency Department Physicians
TRAIL, IP-10, CRP Host-Protein Signature Score Distinguishes Between Viral and Bacterial Infection in Sepsis Patients
A Host Signature Based on TRAIL, IP-10, and CRP For Reducing Antibiotic Overuse in Children by Differentiating Bacterial from Viral Infections: A Prospective, Multicentre Cohort Study
A Point-of-Need Platform for Rapid Measurement of a Host-Protein Score that Differentiates Bacterial from Viral Infection: Analytical Evaluation
Differential Serum and Urine CRP, IP-10, and TRAIL Levels in Pediatric Urinary Tract Infection
Cost impact analysis of novel host-response diagnostic for patients with community-acquired pneumonia in the emergency department
An Immune-Protein Signature Combining TRAIL, IP-10 and CRP for Accurate Prediction of Severe COVID-19 Outcome
An immune-protein signature combining TRAIL, IP-10 and CRP for accurate prediction of severe COVID-19 outcome
Niv Samuel Mastboim, Alon Angel, Oded Shaham, Tahel Ilan Ber, Roy Navon, Einav Simon, Michal Rosenberg, Yael Israeli, Mary Hainrichson, Noa Avni, Eran Reiner, Paul Feigin, Kfir Oved, Boaz Tadmor, Pierre Singer, Ilya Kagan, Shaul Lev, Dror Diker, Amir Jarjou’i, Ramzi Kurd, Eli Ben-Chetrit, Guy Danziger, Cihan Papan, Sergey Motov, Ma’anit Shapira, Michal Stein, Adi Klein, Tanya M Gottlieb, Eran Eden
doi: https://doi.org/10.1101/2021.06.27.21259196
Distinguishing Bacterial Versus Non-Bacterial Causes of Febrile Illness – A Systematic Review of Host Biomarkers
Distinguishing bacterial versus non-bacterial causes of febrile illness – A systematic review of host biomarkers
B. Leticia Fernandez-Carballo; Camille Escadafal; Emily MacLean; Anokhi J. Kapasi; Sabine Dittrich
REVIEW | VOLUME 82, ISSUE 4, P1-10, APRIL 01, 2021
Observational Cohort Study of IP-10’s Potential as a Biomarker to Aid in Inflammation Regulation Within a Clinical Decision Support Protocol for Patients with Severe COVID-19
Observational cohort study of IP-10’s potential as a biomarker to aid in inflammation regulation within a clinical decision support protocol for patients with severe COVID-19
Shaul Lev, Tamar Gottesman, Gal Sahaf Levin, Doron Lederfein, Evgeny Berkov, Dror Diker,Aliza Zaidman, Amir Nutman, Tahel Ilan Ber, Alon Angel, Lior Kellerman, Eran Barash, Roy Navon, Olga Boico, Yael Israeli, Michal Rosenberg, Amir Gelman, Roy Kalfon, Einav Simon, Noa Avni, Mary Hainrichson, Oren Zarchin, Tanya M. Gottlieb, Kfir Oved, Eran Eden, Boaz Tadmor
PLOS ONE | https://doi.org/10.1371/journal.pone.0245296 January 12, 2021
Update of a Clinical Prediction Model for Serious Bacterial Infections in Preschool Children by Adding a Host-Protein-Based Assay: A Diagnostic Study
Automating a New Host-protein Assay for Differentiating Bacterial from Viral Infection to Reduce Operator Hands-on Time
Automating a New Host-protein Assay for Differentiating Bacterial from Viral Infection to Reduce Operator Hands-on time.
Future Science
Shapira M, Boico O, Cohen A, Sagi R, Aharon A, Navon R, Kronenfeld G, Maler K, Pri-Or E, Stein M, Klein A, Eden E, Oved K
BioTechniques. 2018 Aug;65:93-95. doi: 10.2144/btn-2018-0028
Antibiotic Misuse in Respiratory Tract Infections in Children and Adults—A Prospective, Multicentre Study (TAILORED Treatment)
A host-protein signature is superior to other biomarkers for differentiating between bacterial and viral disease in patients with respiratory infection and fever without source: a prospective observational study.
Ashkenazi-Hoffnung L, Oved K, Navon R, Friedman T, Boico O, Paz M, Kronenfeld G, Etshtein L, Cohen A, Gottlieb TM, Eden E, Chistyakov I, Srugo I, Klein A, Ashkenazi S, Scheuerman O.
Eur J Clin Microbiol Infect Dis. 2018 Apr 26. doi: 10.1007/s10096-018-3261-3
A Novel Host-Protein Assay Outperforms Routine Parameters for Distinguishing Between Bacterial and Viral Lower Respiratory Tract Infections
A novel host-protein assay outperforms routine parameters for distinguishing between bacterial and viral lower respiratory tract infections.
Stein M, Lipman-Arens S, Oved K, Cohen A, Bamberger E, Navon R, Boico O, Friedman T, Etshtein L, Paz M, Gottlieb TM, Kriger O, Fonar Y, Pri-Or E, Yacobov R, Dotan Y, Hochberg A, Grupper M, Chistyakov I, Potasman I, Srugo I, Eden E, Klein A
Diagn Microbiol Infect Dis. 2018 Mar;90(3):206-213. doi: 10.1016/j.diagmicrobio.2017.11.011
Validation of a Novel Assay to Distinguish Bacterial and Viral Infections
Isaac Srugo, MD, et al.
Assessing the Febrile Child for Serious Infection: A Step Closer to Meaningful Rapid Results.
Assessing the Febrile Child for Serious Infection: A Step Closer to Meaningful Rapid Results.
David W. Kimberlin, Claudette L. Poole
Pediatrics. 2017 Oct;140(4). pii: e20171210. doi: 10.1542/peds.2017-1210
A Host-Protein Based Assay to Differentiate Between Bacterial and Viral Infections in Preschool Children (OPPORTUNITY): A Double-Blind, Multicentre, Validation Study
Diagnostic Accuracy of a TRAIL, IP-10 and CRP Combination for Discriminating Bacterial and Viral Etiologies at the Emergency Department
Diagnostic Accuracy of a TRAIL, IP-10 and CRP Combination for Discriminating Bacterial and Viral Etiologies at the Emergency Department.
Eran Eden, Isaac Srugo, Tanya Gottlieb, Roy Navon, Olga Boico, Asi Cohen, Ellen Bamberger, Adi Klein, Kfir Oved
J Infect. 2016 Aug;73(2):177-80. doi: 10.1016/j.jinf.2016.05.002
A Multifaceted ‘omics’ Approach for Addressing the Challenge of Antimicrobial Resistance
A Multifaceted ‘omics’ Approach for Addressing The Challenge of Antimicrobial Resistance.
A Multifaceted ‘omics’ Approach for Addressing The Challenge of Antimicrobial Resistance.
Cohen A, Bont L, Engelhard D, Moore E, Fernández D, Kreisberg-Greenblatt R, Oved K, Eden E, Hays JP
Future Microbiol. 2015;10(3):365-76. doi: 10.2217/fmb.14.127
A Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infections