Learning Center
| 25 Jul 2023
| 02 Nov 2023
Diagnostic Accuracy of a Bacterial Versus Viral Host-protein Test for Children Hospitalized With Acute Infections
26 Nov 2025
Bont, Louis MD, Klein, Adi MD, Stein, Michal MD, Mor, Meirav MD; Srugo, Isaac MD; Lebedenko, Boris MSc, et al.
Abstract: MeMed Severity™: A Host-Protein Signature for Risk Stratification in Emergency Department Patients with Suspected Sepsis
12 Oct 2025
A. Angel, O. Shaham, E.Reiner, R. Navon, T. Gottlieb, S. Halabi, et al.
Abstract: Using a Host-Protein Test (Based on TRAIL/IP-10/CRP) to Assess the Likelihood of Bacterial Infection in Patients with Suspected Sepsis
12 Oct 2025
R. Navon, A. Angel, B. Lebedenko, L. Kellerman, T. Gottlieb, E. Eden
Abstract: Differentiating Bacterial Versus Viral Infections in Elderly Patients With Suspected UTI: A Pilot Study
16 Sep 2025
A.J. Singer, M. Taylor, D. LeBlanc, T. Barbiera, M. Ma, W.F. Peacock
Abstract: Impact of a Host-Protein Test on Antibiotic Use and Healthcare Costs in LRTI: JUNO RCT Sub-Analysis
16 Sep 2025
A.J. Singer, E.R. Kean, H. Ring, C.M. Cannon, S. Motov, J. Thoppil, et al.
Abstract: Host-Protein Test in Routine Emergency Department Practice: Impact on Antibiotic Prescription, Admission, and Emergency Department Return
16 Sep 2025
H. Bodenstein ∙ M. Ghitan ∙ T. Gottlieb ∙ L. Kellerman ∙ B. Lebedenko ∙ S. Motov ∙ A. LoVerde
Abstract: Pilot Evaluation of a Host-Protein Test in Emergency Department Patients Who Trigger a Sepsis Alert
16 Sep 2025
J. Wilson, M. O’Driscoll, S. Silbert, S. Young, A. Chamani, B. Vanfleet
Abstract: A Novel Host-Response Tool for Risk Stratification in Adults With Suspected Sepsis: MeMed Severity
16 Sep 2025
T. Aufderheide, S. Motov, S. Shiber, E. Giamarellos, P. Hausfater, L. Velly, et al.
Diagnostic Insights: Pneumonia, Precision and Pounds: The Economic Power of Accurate Diagnosis with MeMed BV
8 May 2025
David Myers, Sarah Nourse
Effect of Host- Protein Test (TRAIL/IP- 10/CRP) on Antibiotic Prescription and Emergency Department or Urgent Care Center Return Visits: The JUNO Pilot Randomized Controlled Trial
27 Apr 2025
Singer A, Hollander J, Kean E, Ring H, et al.
From Pathogen to Infectious Disease Diagnosis: Test Determines Between Bacterial and Viral Infections in 15 Minutes
15 Apr 2025
By Rodney E. Rohde, PhD, SV/SM/MB(ASCP)CM, FACSc Eran Eden, PhD
Host-response testing with MeMed BV in Community-Acquired Pneumonia: An Economic Evaluation From the UK NHS Perspective
27 Feb 2025
Gregg E, Graziadio S, Green W, Afonso D, et al.
Development of a Reference Standard to Assign Bacterial Versus Viral Infection Etiology Using an All-Inclusive Methodology for Comparison of Novel Diagnostic Tool Performance
27 Feb 2025
Allen C, J Deanehan K, Dotan Y, A Eisenberg M, M Fine A, et al.
Implementation of a Rapid Host-Protein Diagnostic Test for Distinguishing Bacterial and Viral Infections in Adults Presenting to Urgent Care Centers: A Pragmatic Cohort Study
27 Feb 2025
Kalmovich B, Rahamim-Cohen D, Yehoshua I, Kivity S, et al.
Poster: Implementation of a Host-Protein Test (MMBV) Into Routine Care for Children Hospitalized with Symptoms of Lower Respiratory Tract Infection
26 Nov 2024
Nir V, Konfino V, Cohen N, Levy E., Shapira M., Stein M., Klein A
Poster: Diagnostic Performance of a Rapid Host-Protein Test (MeMed BV) In Detecting Bacteremia in Children
26 Nov 2024
Kellerman L. Eden E, Gottlieb T, Navon R, Stein M, Srugo I, et al.
Abstract: Real World Experience Using a Rapid Test to Distinguish Bacterial From Viral Infection in the Emergency Department
26 Nov 2024
C. Pun ∙ D. Abu-Jubara ∙ J. Maggiore
Abstract: Host-Protein Test Impact on Antibiotic Prescription Rates in Adults With Suspected Lower Respiratory Tract Infection
26 Nov 2024
A. Singer ∙ J. Hollander ∙ S. Motov ∙ C. Cannon ∙ H. Ring ∙ J. Thoppil, et al.
Abstract: Verification and Validation Study for a Host Response Assay Based on TRAIL, IP-10, and CRP: Application to Pediatric Emergency Department
26 Nov 2024
A M Styer, N Anderson, S Alander, S Gowtham, K Jeffreys, J Vodzak, J W Hirschhorn, D M Wolk
Abstract: A Rapid Host-Response Test Supports Antimicrobial Stewardship at a Micro-Hospital Emergency Department
26 Nov 2024
B DuChateau, S Murphy, C Tarr, T Gottlieb, S Spies
Abstract: The Association of the MeMed BV Test with Radiographic Pneumonia in Children
26 Nov 2024
Ramgopal S.
Abstract: Impact of a Novel Host-Response Diagnostic on ED Antibiotic Decision-Making
26 Nov 2024
Mann E., Wilson C., Klein E., Saheed M., McBryde B., Rothman R., et al.
ABSTRACT: Diagnostic Test Accuracy of TRAIL, IP-10 and C-RP Biomarker Combination (MeMed BV Test) for Discrimination of Viral vs. Bacterial Infections Among Emergency Department Patients with Febrile Illness: A Systematic Review and Meta-Analysis
20 Oct 2024
Kandula M, Farrell J
ABSTRACT: An Adjunct Bio-Array that Rapidly Differentiates Viral from Bacterial Sources Can Improve Quality of Care in Oncology Patients Presenting to Emergency Departments (EDs) with Respiratory Illnesses
20 Oct 2024
Robinson D, Gardiner C, Furbacher J, Vu M, Ticas D, Bakunas C, et al.
PUBLICATION: Assessment of MeMed BV Assays for Differentiating Between Bacterial and Viral Respiratory Infections
20 Oct 2024
Carroll K
Abstract: Bacterial Versus Viral Score Test: Evaluating Potential for Antibiotic Stewardship in Pediatrics
1 Jul 2024
Niles, D., Binns H., Chokkalla A., Devaraj S.
Abstract: Real – World Impact of MeMed BV, a Rapid Host Response Test for Distinguishing Bacterial and Viral Infections, in an Urgent Care Network
4 Jun 2024
Shapiro Ben David, S, Rahamim - Cohen, D, Yehoshua, I, Kivity, S, Kalmovich, B.
PUBLICATION: A Rapid Host–Protein Test for Differentiating Bacterial from Viral Infection: Apollo Diagnostic Accuracy Study
8 May 2024
Bachur R, Kaplan S, Arias C, Ballard N, Carroll K, Cruz A, et al.
PUBLICATION: Validation of a Whole Blood Machine Learning Strategy for Distinguishing Between Bacterial and Viral Infection in a Pediatric Hospital Setting
24 Mar 2024
Ibrahim R, Ona H, Chokkalla A, Tam E, Devaraj S
PUBLICATION: Natural Variability of TRAIL, IP-10, and CRP in Healthy Adults – The “HERACLES” Study
5 Feb 2024
Langedijk A, Rengerink K, Harding E, Wensing A, Slooten R, Israeli Y, et al.
PUBLICATION: Host Biomarkers and Combinatorial Scores for the Detection of Serious and Invasive Bacterial Infection in Pediatric Patients with Fever Without Source
5 Dec 2023
Lacroix L, Papis S, Mardegan C, Luterbacher F, L’Huillier A, Sahyoun C, et al.
ABSTRACT: Real-World Impact of a Novel Host Response Test for Distinguishing Between Bacterial and Viral Infections in Pediatric Patients at Ten Urgent Care Centers
27 Nov 2023
Shapiro Ben David S, Rahamim-Cohen D and Kalmovich B.
PUBLICATION: Diagnostic Accuracy of a Real-Time Host-Protein Test for Infection
2 Nov 2023
Klein A, Shapira M, Lipman-Arens S, Bamberger E, Srugo I, Chistyakov I, and Stein, M.
VIDEO PRESENTATION: A Host Response Test (MMBV) for Differentiating Between Bacterial and Viral Infection has the Potential to Improve Antibiotic Stewardship in Patients With Suspected Sepsis
9 Oct 2023
Alon Angel, MD, MeMed
ABSTRACT: Analytical validation of whole blood suitability for MeMed BV, a host-protein test for differentiating between bacterial and viral infection
26 Jul 2023
Hainrichson, M, Simon, E, Kalfon, R, Sanderovich, N, Shamir, N, Kaminr-Israeli, Y, et al.
ABSTRACT: Comparison between blood culture and MeMed BV test results
25 Jul 2023
Zuretti, A, Christian, M, Kogan, R and Motov, S.
ABSTRACT: Validation of a multi analyte immunoassay for distinguishing bacterial vs. viral infections in a pediatric cohort
25 Jul 2023
Chokkalla, AK, Tam, E, Liang, R, Cruz, AT, and Deveraj, S.
PUBLICATION: Host Test Based on TRAIL, IP-10 and CRP for Differentiating Bacterial and Viral Respiratory Tract Infections in Adults: Diagnostic Accuracy Study
1 Jun 2023
Halabi S, Shiber S, Paz M, Gottlieb TM, Barash E, Navon R, et al.
PUBLICATION: Impact on Patient Management of a Novel Host Response Test for Distinguishing Bacterial and Viral Infections: Real World Evidence from the Urgent Care Setting
22 May 2023
Kalmovich B, Rahamim-Cohen D, and Shapiro Ben David S.
PUBLICATION: Validation of a Multi-Analyte Immunoassay for Distinguishing Bacterial vs. Viral Infections in a Pediatric Cohort
16 May 2023
Chokkalla AK, Tam E, Liang R, Cruz AT, Devaraj S.
ABSTRACT: Using MeMed BV® to reduce antibiotic us for low-risk CAP
2 May 2023
Le M, Wilkinson M, Iyer S, and Sanchez V.
ABSTRACT: A new test, based on the measure of three non microbial host proteins, for the differentiation between bacterial and viral infections
17 Apr 2023
Alonso R, Urbina L, Serrano J, Catalán P, Sánchez-Carrillo C, Muñoz P.
ABSTRACT: Clinical impact of a near patient assay capable of discriminating between viral or bacterial lower respiratory tract infection in ambulatory adult patients a pilot study
17 Apr 2023
Karponis D, Shah RA, Ghaffari E, De Butts R, Smith I, Bowen J, et al.
ABSTRACT: A host protein test based on TRAIL, IP-10 and CRP for differentiating between bacterial and viral infection has potential to improve patient selection for blood culture utilization
23 Feb 2023
Neuenschwander J, Tenenbaum T, Esposito S, Kaplan SL, Motov SM, Bachur RG, et al.
PUBLICATION: Bacterial vs. Viral Etiology of Fever: A Prospective Study of a Host Score for Supporting Etiologic Accuracy of Emergency Department Physicians
30 Jan 2023
Mor M, Paz M, Amir L, Levy I, Scheuerman O, Livni G, et al.
PUBLICATION: Expression of TRAIL, IP-10, and CRP in Children With Suspected COVID-19 and Real-life Impact of a Computational Signature on Clinical Decision-making: A Prospective Cohort Study
22 Dec 2022
Fröhlich F, Gronwald B, Bay J, Simon A, Poryo M, Geisel J, et al.·
PUBLICATION: MeMed BV Testing in Emergency Department Patients Presenting With Febrile Illness Concerning for Respiratory Tract Infection
21 Nov 2022
Novak D, Masoudi A, Shaukat B, Kabariti S, Drapkin J, Christian M, et al.
PUBLICATION: BV Score Differentiates Viral From Bacterial-viral Co-infection in Adenovirus PCR Positive Children
9 Nov 2022
Stein M, Shapira M, Bamberger E, Chistyakov I, Dumov D, Srugo I, et al.
ABSTRACT: Real-world Use Of A Novel Host-response Test To Aid Physicians In Distinguishing Between Bacterial And Viral Infections At Outpatient Urgent Care Centers
20 Oct 2022
Shapiro, S, David, B, Rahamim-Cohen, D, and Kalmovich, B.
ABSTRACT: BV Score (based on TRAIL, IP-10 and CRP) Accurately Distinguishes Between Bacterial and Viral Infection in Febrile Children: A Multi-Cohort Analysis
20 Oct 2022
Kaplan, SL, Arias, CA, Bachur, RG, Ballard, N, Bont, LJ, Cruz, AT, et al.
ABSTRACT: A TRAIL, IP-10, CRP Host-protein Score Distinguishes Viral From Viral-bacterial Co-infections In Adult Patients Testing Positive For Viral Detection
3 Oct 2022
Stas, JI, Arias, CA, Carroll, KC, Gordon, R, Halabi, S, Jacob, T, et al.
ABSTRACT: Host-Protein Score (integrating TRAIL, IP-10, CRP) Distinguishes Between Bacterial And Viral Infection In Suspected Sepsis Patients
12 Sep 2022
Gottlieb, T, Arias, CA, Bachur, R, Esposito, S, Halabi, S, Kaplan, SK, et al.
ABSTRACT: MeMed BV Distinguishes Between Viral And Bacterial Infection In Sepsis Patients
27 Jul 2022
Simon, E, Arias, CA, Bachur, RG, Esposito, S, Halabi, S, Kaplan, SL, et al.
ABSTRACT: Host-Protein Score (Integrating TRAIL, IP-10, CRP) Distinguishes Between Viral and Viral-Bacterial Co-infection in Adult Patients Testing Positive for Viral Detection
27 Jul 2022
Arias, CA, Carroll, KC, Gordon, R, Halabi, S, Jacob, T, Motov, SM, et al.
WEBINAR: Bacterial or Viral from Research to Clinical use of MeMed BV in the Emergency Department
21 Jul 2022
ABSTRACT: Host-protein Score (Integrating TRAIL, IP-10, CRP) Distinguishes Between Viral And Viral-bacterial Coinfection In Adult Patients Testing Positive For Viral Detection
10 Jun 2022
Arias, CA, Carroll, KC, Gordon R, Halabi, S, Jacob, T, Motov, S, et al.
PUBLICATION: TRAIL, IP-10, CRP Host-protein Signature Score Distinguishes Between Viral and Bacterial Infection in Sepsis Patients
31 May 2022
Stas J, Arias CA, Bachur R, Esposito S, Halabi S, Kaplan SK, et al.
ABSTRACT: BV Score’s Performance When Applied According To Indications For Use As Part Of Routine Care For Children Presenting To The Ed With Fever Without Source (Spirit Study Sub Analysis)
9 May 2022
Klein, A, Shapira, M, Orr, Y, Lipman-Arens, S, Bamberger, E, Srugo, I, et al.
ABSTRACT: The Performance Of The BV Score For Differentiating Between Bacterial And Viral Infection Is Robust To Methodological Alternatives In Building The Reference Standard
9 May 2022
Papan, C, Argentiero, A, Esposito, S, and Tenenbaum, T.
ABSTRACT: A Host‐protein Test Based On TRAIL, IP‐10 and Differentiates Between Adenoviral And Bacterial‐Adenoviral Co‐infections In Children With Positive PCR‐adenovirus Detection
9 May 2022
Stein, M, Shapira, M, Bamberger, E, Chistyakov, I, Dumov, D, Srugo, I, et al.
PUBLICATION: A Host Signature Based on TRAIL, IP-10, and CRP for Reducing Antibiotic Overuse in Children by Differentiating Bacterial From Viral Infections: A Prospective, Multicentre Cohort Study
7 May 2022
Papan C, Argentiero A, Porwoll M, Hakim U, Farinelli E, Testa I, et al.
PUBLICATION: A Point-of-need Platform for Rapid Measurement of A Host-protein Score That Differentiates Bacterial From Viral Infection: Analytical Evaluation
26 Apr 2022
Hainrichson M, Avni N, Eden E, Feigin P, Gelman A, Halabi S, et al.
ABSTRACT: Validation Of A Novel Semi-quantitative Immunoassay To Differentiate Bacterial Vs Viral Infections From Serum Samples
23 Apr 2022
Faron, ML, Cruz, A, Mesich, B, Gerstbrein, D, and Ledeboer, NA.
ABSTRACT: MeMed BV Distinguishes Between Viral And Bacterial Infection In Sepsis Patients
23 Apr 2022
Sergey, M, and Motov, MD.
ABSTRACT: TRAIL, IP-10, CRP Host-protein Signature Score Distinguishes Between Viral And Bacterial Infection In Sepsis Patients
10 Apr 2022
Jeroen Stas
PUBLICATION: Differential Serum and Urine CRP, IP-10, and TRAIL Levels in Pediatric Urinary Tract Infection
13 Dec 2021
Ashkenazi-Hoffnung L, Livni G, Scheuerman O, Berger I, Eden E, Oved K, et al.
PUBLICATION: Cost Impact Analysis of Novel Host-response Diagnostic for Patients With Community-acquired Pneumonia in the Emergency Department
18 Nov 2021
Schneider JE and Cooper JT.
ABSTRACT: A Rapidly Measurable Host Assay Comprising TRAIL, IP-10 AND CRP Has Potential To Reduce Antibiotic Overuse Without Increasing Underuse In Adults With Suspected Lower Respiratory Tract Infection
26 Sep 2021
Halabi, S, Shiber, S, Paz, M, Gottlieb, TM, Barash, E, Navon, R, et al.
ABSTRACT: Leveraging The Immune Response To Improve Outbreak Management: Derivation Of A Rapidly Measurable Host-protein Signature For Stratifying Severity Of COVID-19 Patients
26 Sep 2021
Mastboim, NS, Gottlieb, Tm, Shaham, O, Ber, TI, Angel, A, Navon, R, et al.
PUBLICATION: An Immune-protein Signature Combining TRAIL, IP-10 and CRP for Accurate Prediction of Severe COVID-19 Outcome
2 Jul 2021
Mastboim NS, Angel A, Shaham O, Ber TI, Navon R, Simon E, et al.
PUBLICATION: Distinguishing Bacterial Versus Non-bacterial Causes of Febrile Illness – A Systematic Review of Host Biomarkers
18 Feb 2021
Fernandez-Carballo BL, Escadafal C, MacLean E, Kapasi AJ, and Dittrich S.
PUBLICATION: Observational Cohort Study of IP-10’s Potential as a Biomarker to aid in Inflammation Regulation Within a Clinical Decision Support Protocol for Patients With Severe COVID-19
12 Jan 2021
Lev S, Gottesman T, Levin GL, Lederfein D, Berkov E, Diker, et al.
PUBLICATION: A Host-Response Signature Based on TRAIL, IP-10 and CRP Addresses Antibiotic Misuse Driven by Diagnostic Uncertainty
26 Sep 2020
Mastboim N, Argentiero A, Papan C, Gottlieb T, Barash TA, Etshtein L, et al.
PUBLICATION: Update of a Clinical Prediction Model for Serious Bacterial Infections in Preschool Children by Adding a Host-protein-based Assay: A Diagnostic Study
20 Sep 2019
Houten C, van de Maat JS, Naaktgeboren C, Bont L, and Oostenbrink R.
PUBLICATION: Antibiotic Misuse In Respiratory Tract Infections in Children And Adults—A Prospective, Multicentre Study (TAILORED Treatment)
1 Sep 2019
Houten, CB, Cohen, A, Engelhard, D, Hays, JP, Karlsson, R, Moore, et al.
PUBLICATION: Automating a New Host-protein Assay for Differentiating Bacterial From Viral Infection to Reduce Operator Hands-on Time
1 Aug 2018
Shapira M, Boico O, Cohen A, Sagi R, Aharon A, Navon R, et al.
PUBLICATION: A Novel Host-protein Assay Outperforms Routine Parameters for Distinguishing Between Bacterial and Viral Lower Respiratory Tract Infections
1 Mar 2018
Stein M, Lipman-Arens S, Oved K, Cohen A, Bamberger E, Navon R, et al.
PUBLICATION: Assessing the Febrile Child for Serious Infection: A Step Closer to Meaningful Rapid Results
1 Oct 2017
Kimberlin DW and Poole CL.
PUBLICATION: Validation of a Novel Assay to Distinguish Bacterial and Viral Infections
1 Oct 2017
Srugo, I, Klein, A, Stein, M, Golan-Shany, O, Kerem, N, Chistyakov, I, et al.
PUBLICATION: A Host-protein Based Assay to Differentiate Between Bacterial and Viral Infections in Preschool Children (Opportunity): A Double-blind, Multicentre, Validation Study
18 Apr 2017
Houten CB, Groot J, Klein A, Srugo I, Chistyakov I, Waal, W, et al.
PUBLICATION: Diagnostic Accuracy of a TRAIL, IP-10 and CRP Combination for Discriminating Bacterial and Viral Etiologies at the Emergency Department
1 Aug 2016
Eden E, Srugo I, Gottlieb T, Navon R, Boico O, Cohen A, et al.
PUBLICATION: A Multifaceted ‘omics’ Approach for Addressing the Challenge of Antimicrobial Resistance
27 Mar 2015
Cohen A, Bont L, Engelhard D, Moore E, Fernández D, Kreisberg-Greenblatt DR, et al.
PUBLICATION: A Novel Host-Proteome Signature for Distinguishing between Acute Bacterial and Viral Infections
18 Mar 2015
Oved K, Cohen, A, Boico, O, Navon, R, Friedman, T, Etshtein L, et al.